Exzolt 15ml Treatment For Red Mites and Blood Lice

60.00

Exzolt 15ml Treatment For Red Mites and Blood Lice

Experience the benefits of using Exzolt.

  • Induces a rapid and massive decrease in mite populations in a chicken house, with demonstrated 99%+ efficacy
  • Results start within hours of administration, and the two administrations seven days apart span two mite life cycles, thus disrupting mite population dynamics
  • Convenient treatment in the drinking water at a low dose of 0.5 mg/kg BW per treatment day, repeated seven days later
  • Ready-to-use solution (1% fluralaner, 10 mg/mL) for simple dilution in drinking water and easy to measure and mix
  • Effective control against active, blood sucking PRM for at least two weeks following administration. (Follow standard biosecurity measures to prevent mite re-infestation. Wild birds or newly purchased chickens can re-introduce mites two weeks after treatment)
  • Zero egg withdrawal period. A withdrawal period of 14 days after the last administration of Exzolt is required for human consumption of meat and offal
  • Highly active against mite strains resistant to classical acaricides
  • Well tolerated for use in layer hens, pullets and breeders, with a wide margin of safety

A recent study1 showed that PRM severely impacts hen welfare, inducing chronic stress as shown by high corticosterone (stress hormone) levels in blood and feather samples. Following treatment with Exzolt, the drop in mite count was also associated with a significant improvement of stress-induced behaviours. This happens not only at night when the mites are the most active, but also during the day.

7 days

Using Exzolt

Exzolt offers fast and effective mite control in a solution that is easy to mix and administer

  • 1. The easiest way to administer Exzolt is to add it to the first drink of the day.
  • 2. Add the prescribed dose of Exzolt to clean drinking water. The amount of water is not important but as a rough guide use an amount that the chickens will drink in four to six hours. This allows all the chickens to drink without competition.
  • 3. Mix gently to prevent foaming.
  • 4. Wash out the Exzolt container with water twice to remove any traces of Exzolt and to ensure chickens get the full dose.
  • 5. Remove all other drinking sources. Keeping the chickens in the coop or run at this stage might be helpful.
  • 6. Once all the water and Exzolt has been consumed, replenish with normal drinking water. Other water sources can be replaced, and chickens let out as normal.
  • 7. Repeat the treatment once in seven days. The second treatment is essential to ensure the efficacy of Exzolt.

Treatment in the early spring and late summer is recommended as a minimum to keep PRM under control.

1 Thomas E, Temple D, Petersen I. Effect of fluralaner on behavioural stress indicators in laying hens infested with Dermanyssus gallinae. 4th International Symposium on Parasite Infections in Poultry, Vienna, 28-29 June 2019, 36-37.

EMA/389718/2017
EMEA/V/C/004344

Exzolt
fluralaner

This is a summary of the European Public Assessment Report (EPAR) for Exzolt. It explains how the Agency assessed this veterinary medicine to recommend its authorisation in the European Union (EU) and its conditions of use. It is not intended to provide practical advice on how to use Exzolt. For practical information about using Exzolt, animal owners or keepers should read the package leaflet, or contact their veterinarian or pharmacist.

What is Exzolt and what is it used for?

Exzolt is a veterinary medicine used to treat poultry red mite (Dermanyssus gallinae) infestation in pullets (young female chickens), breeders, and layer hens. Poultry red mite is a parasite that feeds on the blood of hens. Red mite infestations can cause irritation and restlessness of the bird, feather pecking, and anaemia (low red blood cell counts). Egg production may also be affected. Exzolt contains the active substance fluralaner.

How is Exzolt used?

Exzolt is available as a solution for use in drinking water and can only be obtained with a prescription. Exzolt is added to drinking water on two occasions, seven days apart. Sufficient Exzolt is added to ensure the required dose is present in the volume of water that the chickens will consume in one day. If another course of treatment is required, the interval between the two courses of treatment should be at least 3 months. For further information, see the package leaflet.

How does Exzolt work?

The active substance in Exzolt, fluralaner, acts as an ‘ectoparasiticide’. This means it kills parasites such as mites that feed on the skin of animals. Fluralaner kills mites by acting on their nervous system after they have ingested the chicken’s blood. It works by interfering with the way that signals are passed between nerve cells (neurotransmission) in the nervous system of parasites, resulting in paralysis and death of the mites.

What benefits of Exzolt have been shown in studies?

Exzolt has been studied in a field study involving 9 farms with poultry red mite infestation, each with two similar houses with 550 to 100,000 chickens per house. One of the houses on each of the farms was treated with Exzolt, and the other house was left untreated. Exzolt reduced the number of mites by more than 99% in pullets and breeders and more than 98% in layers. The duration of effectiveness was between 6 weeks and 8 months, depending on the length of the production cycle and how effectively the farms prevented the re-introduction of new mites into their houses.

What are the risks associated with Exzolt?

There are no known side effects. For the full list of restrictions, see the package leaflet.

What are the precautions for the person who gives the medicine or comes into contact with the animal?
Safety information has been included in the summary of product characteristics and the package leaflet for Exzolt, including the appropriate precautions to be followed by healthcare professionals and animal owners or keepers. Since veterinary medicine may be slightly irritating to the skin and/or eyes, contact with skin, eyes, and mucous membranes (moist body surfaces, such as the lining of the mouth) should be avoided. While handling the product people must not eat, drink, or smoke. Hands and contacted skin should be washed after use of the medicine.

What is the withdrawal period in food-producing animals?

The withdrawal period is the time required after administration of a medicine before an animal can be
slaughtered and the meat used for human consumption. It is also the time required after
administration of a medicine before eggs may be used for human consumption.
The withdrawal period for meat from chickens treated with Exzolt is 14 days.
The withdrawal period for eggs from chickens treated with Exzolt is ‘zero’ days, which means there is
no mandatory waiting time.

Why is Exzolt approved?

The Agency’s Committee for Medicinal Products for Veterinary Use (CVMP) concluded that Exzolt’s
benefits are greater than its risks and recommended that it be approved for use in the EU.

Other information about Exzolt?

The European Commission granted a marketing authorisation valid throughout the EU for Exzolt on
18 August 2017.

The full EPAR for Exzolt can be found on the Agency’s website: ema.europa.eu/Find
medicine/Veterinary medicines/European public assessment reports. For more information about
treatment with Exzolt, animal owners or keepers should read the package leaflet or contact their
Exzolt veterinarian or pharmacist.

This summary was last updated in June 2017.

3 in stock (can be backordered)

Description

Exzolt 15ml Treatment For Red Mites and Blood Lice

Experience the benefits of using Exzolt.

  • Induces a rapid and massive decrease in mite populations in a chicken house, with demonstrated 99%+ efficacy
  • Results start within hours of administration, and the two administrations seven days apart span two mite life cycles, thus disrupting mite population dynamics
  • Convenient treatment in the drinking water at a low dose of 0.5 mg/kg BW per treatment day, repeated seven days later
  • Ready-to-use solution (1% fluralaner, 10 mg/mL) for simple dilution in drinking water and easy to measure and mix
  • Effective control against active, blood sucking PRM for at least two weeks following administration. (Follow standard biosecurity measures to prevent mite re-infestation. Wild birds or newly purchased chickens can re-introduce mites two weeks after treatment)
  • Zero egg withdrawal period. A withdrawal period of 14 days after the last administration of Exzolt is required for human consumption of meat and offal
  • Highly active against mite strains resistant to classical acaricides
  • Well tolerated for use in layer hens, pullets and breeders, with a wide margin of safety

A recent study1 showed that PRM severely impacts hen welfare, inducing chronic stress as shown by high corticosterone (stress hormone) levels in blood and feather samples. Following treatment with Exzolt, the drop in mite count was also associated with a significant improvement of stress-induced behaviours. This happens not only at night when the mites are the most active, but also during the day.

7 days

Using Exzolt

Exzolt offers fast and effective mite control in a solution that is easy to mix and administer

  • 1. The easiest way to administer Exzolt is to add it to the first drink of the day.
  • 2. Add the prescribed dose of Exzolt to clean drinking water. The amount of water is not important but as a rough guide use an amount that the chickens will drink in four to six hours. This allows all the chickens to drink without competition.
  • 3. Mix gently to prevent foaming.
  • 4. Wash out the Exzolt container with water twice to remove any traces of Exzolt and to ensure chickens get the full dose.
  • 5. Remove all other drinking sources. Keeping the chickens in the coop or run at this stage might be helpful.
  • 6. Once all the water and Exzolt has been consumed, replenish with normal drinking water. Other water sources can be replaced, and chickens let out as normal.
  • 7. Repeat the treatment once in seven days. The second treatment is essential to ensure the efficacy of Exzolt.

Treatment in the early spring and late summer is recommended as a minimum to keep PRM under control.

1 Thomas E, Temple D, Petersen I. Effect of fluralaner on behavioural stress indicators in laying hens infested with Dermanyssus gallinae. 4th International Symposium on Parasite Infections in Poultry, Vienna, 28-29 June 2019, 36-37.

EMA/389718/2017
EMEA/V/C/004344

Exzolt
fluralaner

This is a summary of the European Public Assessment Report (EPAR) for Exzolt. It explains how the Agency assessed this veterinary medicine to recommend its authorisation in the European Union (EU) and its conditions of use. It is not intended to provide practical advice on how to use Exzolt. For practical information about using Exzolt, animal owners or keepers should read the package leaflet, or contact their veterinarian or pharmacist.

What is Exzolt and what is it used for?

Exzolt is a veterinary medicine used to treat poultry red mite (Dermanyssus gallinae) infestation in pullets (young female chickens), breeders, and layer hens. Poultry red mite is a parasite that feeds on the blood of hens. Red mite infestations can cause irritation and restlessness of the bird, feather pecking, and anaemia (low red blood cell counts). Egg production may also be affected. Exzolt contains the active substance fluralaner.

How is Exzolt used?

Exzolt is available as a solution for use in drinking water and can only be obtained with a prescription. Exzolt is added to drinking water on two occasions, seven days apart. Sufficient Exzolt is added to ensure the required dose is present in the volume of water that the chickens will consume in one day. If another course of treatment is required, the interval between the two courses of treatment should be at least 3 months. For further information, see the package leaflet.

How does Exzolt work?

The active substance in Exzolt, fluralaner, acts as an ‘ectoparasiticide’. This means it kills parasites such as mites that feed on the skin of animals. Fluralaner kills mites by acting on their nervous system after they have ingested the chicken’s blood. It works by interfering with the way that signals are passed between nerve cells (neurotransmission) in the nervous system of parasites, resulting in paralysis and death of the mites.

What benefits of Exzolt have been shown in studies?

Exzolt has been studied in a field study involving 9 farms with poultry red mite infestation, each with two similar houses with 550 to 100,000 chickens per house. One of the houses on each of the farms was treated with Exzolt, and the other house was left untreated. Exzolt reduced the number of mites by more than 99% in pullets and breeders and more than 98% in layers. The duration of effectiveness was between 6 weeks and 8 months, depending on the length of the production cycle and how effectively the farms prevented the re-introduction of new mites into their houses.

What are the risks associated with Exzolt?

There are no known side effects. For the full list of restrictions, see the package leaflet.

What are the precautions for the person who gives the medicine or comes into contact with the animal?
Safety information has been included in the summary of product characteristics and the package leaflet for Exzolt, including the appropriate precautions to be followed by healthcare professionals and animal owners or keepers. Since veterinary medicine may be slightly irritating to the skin and/or eyes, contact with skin, eyes, and mucous membranes (moist body surfaces, such as the lining of the mouth) should be avoided. While handling the product people must not eat, drink, or smoke. Hands and contacted skin should be washed after use of the medicine.

What is the withdrawal period in food-producing animals?

The withdrawal period is the time required after administration of a medicine before an animal can be
slaughtered and the meat used for human consumption. It is also the time required after
administration of a medicine before eggs may be used for human consumption.
The withdrawal period for meat from chickens treated with Exzolt is 14 days.
The withdrawal period for eggs from chickens treated with Exzolt is ‘zero’ days, which means there is
no mandatory waiting time.

Why is Exzolt approved?

The Agency’s Committee for Medicinal Products for Veterinary Use (CVMP) concluded that Exzolt’s
benefits are greater than its risks and recommended that it be approved for use in the EU.

Other information about Exzolt?

The European Commission granted a marketing authorisation valid throughout the EU for Exzolt on
18 August 2017.

The full EPAR for Exzolt can be found on the Agency’s website: ema.europa.eu/Find
medicine/Veterinary medicines/European public assessment reports. For more information about
treatment with Exzolt, animal owners or keepers should read the package leaflet or contact their
Exzolt veterinarian or pharmacist.

This summary was last updated in June 2017.

Additional information

Weight .15 kg

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